Photostability Chambers, Photo Stability Test Chambers, Photostability Test Chambers, Pharmaceutical Photostability Test Chambers

Weiber Photostability Test Chambers are widely used for confirmatory studies as per ICH GUIDELINES (ICH Q1B) for direct comparison of drug substance under controlled environmental conditions, where samples are exposed to light illumination level of 1.2 million lux ,which is effectively controlled through a programmable illumination controller and ulta violet light module incorporated in the same diffuser module with protection coating, designed to provide a UV light energy which can also be controlled from 200 watt hour per sq m.to allow direct comparisons to be made between the drug substance and drug product.

Material of Construction:

Castor wheel mounted cabinet is double walled with inner chamber of Stainless steel sheet of grade SS 304 and outer wall of heavy gauge PCRC steel. sheet duly degreased and pre treated with primers for rust proofing duly painted with attractive stove enamel or powder coated.

Temperature Range:

10 Degree C to 60 degree C (Accuracy: + 0.5o C)

Temperature Control:

The temperature inside the photo stability test chamber is controlled by intelligent programmable temperature controller and indicator. This controller is based on the microcontroller nano watt technology and its ergonomic design suits for any specific requirement of the photostability test chambers like Data logger facility, Thermal and DOT Matrix interface, direct data load facility in computer office automation software like MS-Word and Excel and many other features listed in the specification bellow.

Humidity Range

40% to 95% RH (Accuracy: + 2%)

Accurate Micro processor Based Humidity Control System.

The WEIBER” Photo Stabiliy Chamber uses a microprocessor based, electronic humidity sensor detector is an exact logarithmic function of the humidity concentration in the environment of the chamber between source and detector. Advanced design provides a very stable drift-free output requiring less frequent calibration.

Illumination

Our photostability test chamber/pharmaceutical photostability test chamber conforms to the illumination requirement as per the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) ICH GUIDELINES (ICH Q1B). The unit is provided with four fluorescent light mounted in a diffuser enclosure at the top of the chamber providing minimum illumination level of 1.2 million lux, Which iseffectively controlled through a programmable illumination controller. This unit is combined with a ulta violet light module incorporated in the same diffuser module with protection coating, designed to provide a UV light energy which can also be controlled from 200 watt hour per sq.

1) Heater Mode

This LED indicates the heating system on condition and it light up when the set temperature is higher than the ambient temperature.

2) Cooling Mode:

This LED indicates the cooling system on condition and it light up when the set temperature is lower than the ambient temperature.

3) Temperature Alarm:

This LED indicated the extreme Ambient condition and the temperature failure condition.

4) Audio Alarm :

This Alarm indicates the visual alarm and indiactes any failure and Temperature overshoot conditions.

5) Door Open :

Visual indication with door open conditions.

6) A.C Power failure :

This visual indicator light up when the mains power fail and the system working in the battery mode.

7) Low battery indicator :

This LED indicates the battery backup status, This LED indicates when the battery charge capacity available at 25% of the total charge.

8) UP :

Count up key.

9) SET :

This is a set button to set any parameter on the screen, by pressing of this key a cursor blink on the corresponding parameter, So you can select any desired parameter and use UP and Down key to set specific value/setting.

10) Down :

Down count key

11) ESC :

This key is used to exit from any menu, you are working right now.

12) Print/Data download :

This key is used to transfer the stored data into the printer or Data download facility in the computer MS Excel/Word and Hyperterminal software.

13 ) Display Unit :

This unit is a user intertractive interface system for easy operation and it displays the parameter like DATE, TIME, Ambient Temperature, Compressor ON Delay Time, Read and Set Temperature.

14) Temperature Display :

This seven segment display indicates the read temperature value inside the chamber.

SYSTEM SETTING

DATE and TIME : From normal operational mode, press SET key ones, The cursor blinks at DATE (20), and for second press of KEY SET the cursor blinks at MONTH ( 12 ), and similary on Third press of key SET cursor blinks at YEAR and repeat the steps to move to any parameter. Similary you move cursor on any parameter and set desired value for system operation., To increase any parameter use UP key and to decrease any parameter use DOWN key. After completion of all correct setting press ESC key to return back to the main menu.

Optional Features : (Can Be incorporated At Extra Cost If Desired)

• Temperature set point controls relays for refrigeration compressor and evaporator fan.
• Relays rated min. 200VAC: (a) Compressor: min. 8 A, min. 60 LRA, (b) Fan: min. 4 A, (c) High/low temp alarm.
• Audio and Visual Alarm. Programmable.
• Alarm mute w/ ring back in 5 minutes.
• Touch Button Control for Alarm Mute/Ring Back.
• Keyed alarm silence switch.
• External Keyed Alarm Mute. Alternate: Supervisor programmable code.
• Door Buzzer alarm.
• IR Sensor/ Micro Switch Based Door open Alarm. Adjustable or fixed 30s delay before alarm.
• Power failure alarm: Automatic Power detection and Audio Visual Alarm. Adjustable or fixed 15 min delay before alarm.
• Programmable temp range: Touch Button Control to Program Temperature. User Settable.
• Battery backup: Automatic Battery Charging Facility inbuilt in circuit. Provides up to 24 hr of display power.
• Mounted temp probe.
• Dual PT-100 sensor With Ambient Sensing by Semi-conductor Temperature Sensor. Set point display (program mode) LCD and Segment Dry contacts( Remote Control ) for central alarming.
• R.F based Remote Alarm System.
• Built-in chart recorder/Thermal Printer standard for blood bank units or data acquisition in the controller memory which can be down loaded on a computer through a suitable world standard interface like RS232 and/or RS485.
• RS-232 I/O Port Provided.
• Serial Thermal Printing facility.
• 24 hr non-volatile temperature Record Storage Capacity, and Record Download facility in MS-WORD/Hyper terminal / MS-Excel.
• Up to 1 MB data storage Facility.
• Seven Day Profile Timer with Real Time Clock.

Insulation :

The gap of 75 mm between the outer and the inner wall is filled with special grade glass wool to prevent thermal losses.

Mineral Glass Wool Insulation:

Glass mineral wool is one of the most environmentally friendly, stable and sustainable insulants available. Glass wool is incombustible by nature. Euro class classification is A. It does not propagate flames and toxic smokes. Thanks to a dense entanglement of materials with a low conduction and trapping a great amount of air, glass wool is a an excellent thermal insulant. The thickest it is the best thermal resistance it has, thus reducing heat losses in our equipments for better sensitivity and economical operations. And its impact on the environment in manufacture, use and disposal is minimal.

Air circulation:

Triple walled back of unit is fitted with two air circulation fans for maintaining temperature uniformly throughout the chamber.

Features of Coaxial Circulation Fan:

• Vacuum impregnated stator winding with dr. back varnish under red baktol.
• non-hygroscopic.
• Best IR value.
• Bright bar (EN - 8 class) shaft.
• Bush bearing of branded companies.
• Surge comparison testing in fans and pumps eliminates into turn short circulating of the stator.
• Pressure die-casted-rotor manufactured with zero error.
• Boats of high accuracy.

Doors

Full view inner glass/perspex door permits inspection of specimens, without disturbing the chamber temperature. Lock and Key arrangement is provided in the double walled outer door.

Illumination:

Unit is fitted with door operated illumination lamp inside the chamber. 40 watt/120 volt replacement light bulb fits inside the illumination cavity of the chamber.

Refrigeration Unit:

Refrigeration unit is formed by ISI marked compressor/cooling kit. Of Kioloskar Copeland or Tecumseh.

Features :

• High Energy Efficiency
• Compact
• Ozone-friendly refrigerants
• Proven Technology
• Wide Voltage Range

Technical Matrix For Seed Germinator:

Front Panel:

The front panel is provided with separate indicator lamps for main heating and incoming voltage. Digital Temperature controller cum Indicator and voltmeter.

Shelves:

The unit is supplied with three shelves of stainless steel sheet.

Voltage:

To work on 220/230V A.C. supply.

Internal Dimensions (Standard)